A manga? On an indie comics podcast? 
Don’t worry, we haven’t gone insane (yet.) This is great sci-fi, great detective/mystery, and great story-telling so we’re game! For this series, we cover Pluto by Naoki Urasawa and Takashi Nagasaki based on the original Astro Boy manga. Since Alex and Mike aren’t experts, they partnered with the Tankobon podcast for this 4-episode series. 
The podcast covers two volumes at a time. You can purchase all eight volumes in beautiful paperback or read for free at plutomanga.com. The spoiler-free synopsis is:
Pluto follows the Europol robot detective Gesicht in his attempts to solve the case of a string of robot and human deaths around the world where all the victims have objects shoved into or positioned by their heads, imitating horns. The case becomes more puzzling when evidence suggests a robot is responsible for the murders, which would make it the first time a robot has killed a human in eight years. All seven of the great robots of the world, the most scientifically advanced which have the potential to become weapons of mass destruction, seem to be the killer’s targets, and the murdered humans are connected to preserving the International Robot Laws which grant robots equal rights. – Wikipedia